Born and raised in China, Serene came to Canada at the age of nineteen. She obtained her undergraduate degree in Biology and Chemistry at Ryerson Polytechnic University. She then entered the dental school at the University of Toronto (U of T) with an entrance scholarship. In 2001, she graduated from the Faculty of Dentistry at U of T with honors. She then completed one year of residency program in a hospital in the United States. Upon returning to Canada, Serene worked in multiple rural practices before starting her own practice in 2007.
Serene is fluent in English, Cantonese and Mandarin. She and her husband currently live in the south part of Ottawa. In her leisure time, she enjoys cooking, reading and spending time with her two children.